منابع مشابه
Parasite Carbohydrate Vaccines
Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine development, given the proven success of carbohydrate vaccines to combat bacterial infections. We will review the key components of carbohydra...
متن کاملAnti-parasite vaccines.
Introduction Many viral and bacterial diseases are now controlled, at least in developed countries, by vaccination; indeed, smallpox has been eradicated from the earth by this strategy. Despite the fact that three-quarters of the global population currently harbour single or multiple parasitic infections, we have at present no effective vaccines against these ancient scourges of mankind. For ma...
متن کاملParasite vaccines: the new generation.
Parasites cause some of the most devastating and prevalent diseases in humans and animals. Moreover, parasitic infections increase mortality rates of other serious non-parasitic infections caused by pathogens such as HIV-1. The impact of parasitic diseases in both industrialised and developing countries is further exacerbated by the resistance of some parasites to anti-parasitic drugs and the a...
متن کاملBioinformatic Approach for Identifying Parasite and Fungal Candidate Subunit Vaccines
In silico genome analysis enables systematic identification of potential antigens within a pathogen. Of primary importance is the accuracy of computer algorithms used for antigen prediction. Most bioinformatics tools are based on sequence alignment and are not able to predict truly novel antigenic proteins which lack similarity to existing antigens or which encode antigenicity in a cryptic mann...
متن کاملInfection and treatment immunizations for successful parasite vaccines
Since the advent of techniques for the expression of recombinant peptide antigens, the availability of human vaccines for parasitic diseases has been 'imminent'. Yet vaccines based on recombinant proteins are still largely aspirations, not realities. It is now apparent that vaccine development needs additional knowledge about host protective immune response(s), antigen characteristics, and the ...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2017
ISSN: 2235-2988
DOI: 10.3389/fcimb.2017.00248